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Clinical Pain 2021; 20(2): 105-121

Published online December 31, 2021 https://doi.org/10.35827/cp.2021.20.2.105

Copyright © Korean Association of Pain Medicine.

Clinical Study on Safety, Clinical Indicators of Polydioxanone Sutures Inserted into Vastus Medialis Muscle in Degenerative Knee Osteoarthritis

무릎 관절염 환자에서 안쪽넓은근에 폴리디옥사논 봉합사 시술 연구

Ki-Choul Kim, M.D.1, Hyung-Jun Lee, M.D.1, Kil-Yong Lee, M.D.2 and Hee-Gon Park, M.D., Ph.D.1

김기철1ㆍ이형준1ㆍ이길용2ㆍ박희곤1

1Department of Orthopedic Surgery, Dankook University College of Medicine, Cheonan
2Department of Neurosurgery, Seoul Yes Hospital, Yongin, Korea

단국대학교병원 정형외과1 서울예스병원 신경외과2

Received: October 29, 2021; Revised: November 12, 2021; Accepted: November 22, 2021

Abstract

Objective: Physiologically, the vastus medialis muscle is the first muscle to undergo muscle atrophy, and it was thought that pain in patients with knee osteoarthritis could be reduced if this muscle could be strengthened and stabilized. The purpose of this study was to prove the effectiveness in knee osteoarthritis using polydioxanone sutures that have been tried in other musculoskeletal areas. Method: Forty knee osteoarthritis patients voluntarily participated in the study, and divided into 30 polydioxanone suture needle (MEST-B2375 produced by Ovmedi Co.) and 10 sham needle (without suture). And the needles were inserted into the vastus medialis muscle. In all patients, safety evaluation including blood tests and ultrasonography as well as efficacy evaluation including isometric maximal contractile strength of quadriceps muscle, weight bearing pain, impression of change, quadriceps angle, rescue drug intake were evaluated up to 30 weeks after the procedure. Results: Isometric maximal contractile strength showed a significant improvement at 4 weeks after the procedure in the polydioxanone suture group, and the weight-bearing pain showed a significant improvement at every visit in the polydioxanone suture group compared with baseline values. Patient global impression of change score showed significant improvement at 20 and 30 weeks, and clinical score showed improvement at every visit. Conclusion: Insertion of polydioxanone sutures showed improvement in muscle strength and knee pain by supporting and fixation of the vastus medialis muscle in patients with degenerative knee osteoarthritis. Insertion of polydioxanone sutures is considered to have a therapeutic effect in knee osteoarthritis patients.

KeywordsOsteoarthritis, Polydioxanone, Strength, Pain, Ultrasonography

Korean Association of Pain Medicine

Vol.22 No.2
December 2023

eISSN: 2765-5156

Frequency: Semi Annual

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